insaf - Methods and Equipment

Here you will find an overview of our broad-spectrum methodologies in applied clinical airway research. Results from basic and clinical research at insaf are regularily published in peer-reviewed medical journals or at conferences and meetings. References

Pulmonary Function Analysis

  • Whole-body Plethysmography and Spirometry
  • Diffusion Capacity (DCO)
  • Rhinomanometry
  • Spiroergometry
  • transcutaneous Oxygensaturation

Monitoring of Inflammation

  • exhaled Nitric Oxide (eNO)
  • induced Sputum including Cytology and soluble Mediator Analysis
  • nasal Lavage including Cytology and soluble Mediator Analysis
  • Exhaled Breath Condensate (EBC)
  • Urinalysis of Mediators (e.g. Leukotrienes, Prostaglandines)
  • Bronchoscopy and bronchoalveolar Lavage

Airway Challenge Models

  • non-specific bronchial challenge (Histamine, Methacholine,
    Adenosine, cold-air and Exercise)
  • specific Allergen Challenge (bronchial and nasal)

In house-Monitoring

  • 7 Patient Rooms
  • 24h+ Pharmacokinetics
  • 24h+ Pharmacodynamics
  • Urine Collection
  • Cardiac Monitoring

Safety Lab Analysis

  • Point-of-Care Analysis of Electrolytes, Glucose
  • Full standard Lab Analysis by external Lab (LaborMed GmbH, Wiesbaden)